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Faculty of Science

Department of Physics & Astronomy

Dr. Ed Lyman - University of Delaware

Description

Title: You are what you eat (and there are biophysical consequences)


Speaker: Dr. Ed Lyman


Institute: University of Delaware


Location: ABB 102




Description:


Your cell membranes are made mostly of lipids, the class of biological macromolecule that includes fat, oil, and wax. This lipidome" is a complex mixture of some 800 different types of lipid which changes with your diet and with the administration of lipid synthesis drugs like statins. Altering the lipid composition of a membrane changes its biophysical properties such as thermodynamic phase, fluidity, viscosity, and curvature stress. Changes in biophysical properties may in turn affect cellular functions like signaling, which often relies on the diffusive encounter of membrane-bound receptors. I will give an overview of the state of membrane biophysics, with a particular focus on recent experimental breakthroughs which admit measurements of lipid diffusion with unprecedented spatiotemporal precision. I will then discuss our own efforts to use modeling approaches in collaboration with experimental colleagues to rationalize lipid and protein spatiotemporal organization in model membranes, and our plans to extend these approaches to interpret recent measurements on live cell membranes.


http://web.physics.udel.edu/about/directory/faculty/edward-r-lyman

Location information

1280 Main St W, Hamilton, ON L8S 4L8, Canada

Country
Canada
County
Ontario
City
Hamilton L8S 4L8
Street
1280 Main Street West

McMaster University - Faculty of Science

Mailing Address

Department of Physics & Astronomy,
McMaster University

ABB-241
1280 Main Street West
Hamilton, Ontario, Canada
L8S 4M1

Contact Information

Telephone Inquiries:
+1 (905) 525-9140 ext.24559
Fax:
(905) 546-1252
Email Inquiries:
physics@mcmaster.ca

McMaster University - Faculty of Science

Mailing Address

Department of Physics & Astronomy,
McMaster University

ABB-241
1280 Main Street West
Hamilton, Ontario, Canada
L8S 4M1

Contact Information

Telephone Inquiries:
+1 (905) 525-9140 ext.24558
Fax:
(905) 546-1252
Email Inquiries:
physics@mcmaster.ca