Date/Time
Date(s) - 23/11/2022
3:30 pm - 4:30 pm

Date: 23 November 2022
Time: 3:30 pm
Location: ABB 102

Guest: Dr. Gonca Erdemci Tandogan
Assistant Professor
Western University

Title: Computational Modelling of Developing Tissues

Abstract:
Tissue material properties can change drastically during embryonic development, reminiscent of rigidity transitions in physics. However, measuring the impact of transitions on cell behaviours or learning how to control the transitions is challenging experimentally. Theoretical and computational models provide new powerful tools to determine the impact of tissue material properties on cell behaviour and offer hypotheses on how to control the transitions. In this talk, I will introduce background on a commonly used tissue model, vertex models. I will highlight recent studies on the role of collective tissue mechanics in development and disease. I will then present our research on developing computational models to study the tissue material properties and their impact on cellular functions and coordination thereof.